How can I do the dephthaloylation in Organic chemistry?

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organic chemistry
Masomeh E asked:


with Hydrazine

Nicholas

One Response to “How can I do the dephthaloylation in Organic chemistry?”

  1. Chris Says:

    check out these papers. From the second one:
    “The dephthaloylation of compounds 2 X¼Cl and compounds 2 X¼H
    were performed respectively by using ethylenediamine (2 eq.) and methylhydrazine
    (1.5 eq.) in THF. As expected, in most of the cases, the tetrachlorophthalimide
    group was removed more easily than the unsubstituted one,
    leading to the formation of compounds 3 in excellent to good yields.”