http://mncu.org/chemistry/how-can-i-do-the-dephthaloylation-in-organic-chemistry/ Chemistry Discussion Thu, 09 Sep 2010 13:36:43 +0000 http://wordpress.org/?v=2.6.3 http://mncu.org/chemistry/how-can-i-do-the-dephthaloylation-in-organic-chemistry/#comment-483 Chris Fri, 30 Jan 2009 22:59:34 +0000 http://mncu.org/chemistry/how-can-i-do-the-dephthaloylation-in-organic-chemistry/#comment-483 check out these papers. From the second one: "The dephthaloylation of compounds 2 X¼Cl and compounds 2 X¼H were performed respectively by using ethylenediamine (2 eq.) and methylhydrazine (1.5 eq.) in THF. As expected, in most of the cases, the tetrachlorophthalimide group was removed more easily than the unsubstituted one, leading to the formation of compounds 3 in excellent to good yields." check out these papers. From the second one:
“The dephthaloylation of compounds 2 X¼Cl and compounds 2 X¼H
were performed respectively by using ethylenediamine (2 eq.) and methylhydrazine
(1.5 eq.) in THF. As expected, in most of the cases, the tetrachlorophthalimide
group was removed more easily than the unsubstituted one,
leading to the formation of compounds 3 in excellent to good yields.”

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